I’m playing through New Vegas right now. I have one of the back buttons assigned to quicksave. I also changed the default camera button to one of the back buttons, because I don’t use it often enough to warrant it being on the bumpers. And I have just assigned one to toggle collision, because sometimes you need that when playing something built in the Gamebryo engine.
To be fair, half of the AAA gaming industry is all about trying to clone the latest successful game with a new coat of paint. Maybe using AI to make these clones will mean that the talented people behind the scenes are free to explore other ideas instead.
Of course in reality, it just means that the largest publishers will lay off a whole lot of people and keep churning out these uninspired games in the name of corporate profits, but it’s nice to dream sometimes.